PDE5 inhibitors prolong the action of cGMP by inhibiting its degradation by the enzyme PDE5, which is found throughout the body. In the penis, PDE5 inhibitors potentiate the effects of cGMP to prolong erections and increase sexual satisfaction.
Is Viagra healthy for men?
Using Viagra can lead to serious risks, too, if you have an underlying medical condition. For instance, men with heart disease who take drugs known as nitrates can develop dangerously low blood pressure if they take Viagra.
Does Viagra cause long term damage?
Most side effects of Viagra are mild and go away quickly as the drug wears off. But in rare cases, some serious side effects can have long-term complications. For example, Viagra can cause prolonged erection. If not treated, this can lead to permanent erectile dysfunction.
What age does a man stop getting a hard on?
The answer to the question, “what age does a man stop getting hard?” is simple: it doesn't exist. Some men in their 90s can still get erections without any trouble, while many men in their 20s struggle with erectile dysfunction.
How many years will Viagra work?
Viagra pills may still work for years after they're first made. But the reduction in chemical activity means that it won't work as well. Expired medications can also grow infectious mold or bacteria. As a rule of thumb, Viagra and other medications have a shelf life of about 2 years.