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what are the benefits of folate

by Kitty Herman DVM Published 3 years ago Updated 2 years ago
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Folate is an essential B vitamin necessary for producing red and white blood cells in bone marrow, producing DNA and RNA, and transforming carbohydrates into energy. Having an adequate amount of folate is especially important during periods of rapid growth, such as pregnancy, infancy, and adolescence.

Full Answer

What foods contain folate?

[38,39] Good sources of folate include:

  • Dark green leafy vegetables (turnip greens, spinach, romaine lettuce, asparagus, Brussels sprouts, broccoli)
  • Beans
  • Peanuts
  • Sunflower seeds
  • Fresh fruits, fruit juices
  • Whole grains
  • Liver
  • Seafood
  • Eggs
  • Fortified foods and supplements

Why is folate good for You?

The Health Benefits of Folate

  1. Supports Normal Fetal Development. Folate plays an integral role in fetal development and the benefits for pregnant women and their offspring cannot be understated.
  2. Promotes Sperm Viability
  3. Great for the Heart. ...
  4. May Reduce the Risk of Stroke. ...
  5. Encourages Normal Cholesterol Levels. ...
  6. Provides Neurological Support. ...
  7. Helps Perinatal Mood Management. ...

More items...

What is folate good for?

Folate, also known as vitamin B9, is a water-soluble vitamin that has many important functions in your body. In particular, it supports healthy cell division and promotes proper fetal growth and development to reduce the risk of birth defects ( 1 ).

How much folate supplement should I take?

The usual recommendation for proper daily folic acid or folate intake is 400 micrograms. Pregnant women should consume more. Folic acid is the synthetic form of the naturally occurring B vitamin folate.

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What does folate do in the body?

Overview. Folate (vitamin B-9) is important in red blood cell formation and for healthy cell growth and function. The nutrient is crucial during early pregnancy to reduce the risk of birth defects of the brain and spine.

Does folate give you energy?

Folate is also known to help with depression, mental fatigue, and irritability because it can be quickly broken down and supply the body with energy. (this is why drinks like 5-hour energy contain B9 along with other B vitamins).

What does folic acid do for a woman?

If a woman has enough folic acid in her body before she is pregnant, it can help prevent major birth defects of her baby's brain and spine. These birth defects are neural tube defects or NTDs. Women need to take folic acid every day, starting before they are pregnant to help prevent NTDs.

What is low folate a symptom of?

When you have anemia, your blood can't bring enough oxygen to all your tissues and organs. Without enough oxygen, your body can't work as well as it should. Low levels of folic acid can cause megaloblastic anemia. With this condition, red blood cells are larger than normal. There are fewer of these cells.

Does folic acid cause weight gain?

There is no evidence that people with adequate blood levels of folic acid will gain weight if they take supplements. However, weight loss is one possible side effect of a folate deficiency.

Is folate good for brain health?

A growing body of evidence suggests that folate and the metabolically related B-vitamins are essential for brain health across all age groups, owing to their specific roles in C1 metabolism and particularly in the production of S-adenosylmethionine, a universal methyl donor essential for the production of ...

Does folic acid help with weight loss?

Our results suggest that excess folic acid may exacerbate weight gain, fat accumulation, and inflammation caused by consumption of a HF diet.

Can you take folic acid and vitamin D together?

No interactions were found between folic acid and Vitamin D3.

When should I take folic acid morning or night?

If you are taking folic acid every day, take it at the same time each day, either in the morning OR in the evening. Take your folic acid tablets with a glass of water. You can take folic acid with or without food. If you forget to take your dose, take it as soon as you remember.

Is B12 the SAMe as folate?

Vitamin B12, also called cobalamin, is found in foods from animals, such as red meat, fish, poultry, milk, yogurt, and eggs. Folate (Vitamin B9) refers to a natural occurring form of the vitamin, whereas folic acid refers to the supplement added to foods and drinks.

Who should not take folic acid?

Folic acid should not be used by people recovering from this procedure. Cancer: Early research suggests that taking 0.8-1 mg of folic acid daily might increase the risk of cancer. Until more is known, people with a history of cancer should avoid high doses of folic acid.

Should you replace B12 or folate first?

Algorithm 1: Serum cobalamin <150 mcg or serum cobalamin 150-250 ng/ml and neurological/neuropsychiatric symptoms with no other identifiable cause or strong clinical suspicion of deficiency (eg SACD) at any B12 level Check folate level but replace B12 first if deficient. Modify any risk factors before proceeding.

Why is folate important?

Folate is important for basic cell function in your body. It helps to form the RNA and DNA that tell our cells what to do. In addition, folate can provide health benefits such as:

What is the best vitamin for the human body?

Folate, also known as vitamin B9 or folic acid, is an essential nutrient for the human body. Many foods naturally contain folate, such as dark-green leafy vegetables, beans, whole grains, and eggs. Food manufacturers add folic acid, the man-made version of folate, to foods to fortify them with this important vitamin.

Does folate help with MTHFR?

Doctors recommend that those with an MTHFR gene mutation supplement with folic acid to both reduce homocysteine levels and reduce the risk of neural tube birth defects. While supplementation of folate can reduce the risk of certain cancers, it can also lead to an elevated risk of prostate cancer.

Can folic acid cause nausea?

Folic acid may cause some mild to moderate side effects, including: Nausea /loss of appetite . Bad taste in the mouth. Confusion. Irritability. Sleep disturbances. Some people may have an allergic reaction to folic acid supplements. Symptoms of an allergic reaction to folate include: Itchiness and redness.

What is the recommended daily amount of folate for adults?

The recommended daily amount of folate for adults is 400 micrograms (mcg).

Why is folic acid important for pregnancy?

The nutrient is crucial during early pregnancy to reduce the risk of birth defects of the brain and spine.

What drugs interact with folic acid?

Possible interactions include: Anticonvulsants. Taking folic acid with fosphenytoin (Cerebyx), phenytoin (Dilantin, Phenytek) or primidone (Mysoline) might decrease the drug's concentration in your blood. Barbiturates.

What are the symptoms of folic acid?

Nausea. Loss of appetite. Confusion. Irritability. Sleep pattern disturbance. People with allergies might have a reaction to folic acid supplements. Warning signs of an allergic reaction include: Skin rash. Itching.

What fruits are rich in folate?

Fruits rich in folate include oranges, lemons, bananas, melons and strawberries. The synthetic form of folate is folic acid. It's in an essential component of prenatal vitamins and is in many fortified foods such as cereals and pastas. A diet lacking foods rich in folate or folic acid can lead to a folate deficiency.

Is it safe to take folate?

Generally safe. For most people, it's best to get folate from food. A balanced diet usually provides all you need. However, folic acid supplements are recommended for women who are planning to become pregnant, could become pregnant, are pregnant or are breast-feeding.

Does folic acid decrease effectiveness?

Barbiturates. Taking folic acid with a drug that acts as a central nervous system depressant (barbiturate) might decrease the drug's effectiveness.

How does folate help the immune system?

3. Boost Immunity: Increased amounts of dietary and supplemental folate can improve immune system function , especially in seniors. The vitamin is known to increase T cells, lymphocytes important in immune response.

Why is folate important for pregnancy?

Here are five of the biggest reasons: 1. Avoid Anemia: Folic acid deficiency has a strong connection to anemia, which is due to a lack of red blood cells.

How Much Folic Acid Do You Need?

Folate is essential for cell growth; women in their childbearing years often require between 600 and 800 micrograms of folate to prevent birth defects such as anencephaly and spina bifida during pregnancy by 50% to 70%. How common are birth defects? Well, every four and a half minutes in the U.S., a mother gives birth to a baby with a defect—that’s 120,000 babies every year. This has got to stop! If a woman has a family history of birth defects, their doctor may recommend four milligrams (4,000 micrograms) of folate. Nursing mothers will even require 500 micrograms of folate for lactation.

What vitamins are good for acne?

5. Soothe Skin Problems: Vitamin B12 and folate are both often used as treatment in people with severe acne. In a recent six-month study, both nutrients were considered low in 100 acne patients. Folate is also known to prevent skin cancer, improve skin firmness, and give the skin a healthy and natural appearance.

When is National Folic Acid Awareness Week?

It doesn’t surprise me that the first full week in January was dedicated to vitamin B9: National Folic Acid Awareness Week was January 4–10. B9 is a water-soluble B-vitamin; folic acid is the synthetic version that you only find in supplements and folate is the natural version found in your food (and also used in some supplements).

How do you know if you are deficient in folate?

How do you know if you are deficient in folate? Antibiotics are known to deplete the B-complex vitamins, including folate. A person with a deficiency may be overly stressed, and have malabsorption and irregular metabolism. Folate can also reduce the risk of stroke, promote normal cholesterol levels and hair growth, and reduce the risk of age-related macular degeneration or colorectal cancer.

Does folic acid help with hair growth?

Folate can also reduce the risk of stroke, promote normal cholesterol levels and hair growth, and reduce the risk of age-related macular degeneration or colorectal cancer. Folate: Health Benefits, Deficiency Symptoms, and Top Food Sources. Sources for Today’s Article:

What is Folate?

Folate is a water-soluble vitamin that is also referred to as vitamin B9.

Where Can You Find Folate in Foods?

Okay. So by now I’ve got you sold on why you need folate in your life…but how do you work more into your diet?

Why is folate important?

Folic acid supplements play an important role in ensuring that vulnerable individuals and those in greater need of folate receive enough. Increasing intake of folate-rich foods is also important as these foods typically also provide plenty of other nutrients that all act together to support good health.

What is the purpose of folate?

Folate is one of the B-vitamins and is needed to make red and white blood cells in the bone marrow, convert carbohydrates into energy, and produce DNA and RNA. Adequate folate intake is extremely important during periods of rapid growth such as pregnancy, infancy, and adolescence. ...

Why is it important to take folic acid during pregnancy?

It is essential to consume enough folic acid during pregnancy to help protect against miscarriage and neural tube defects in the fetus. Recent research has also shown that a father’s folate status before conception may be just as important. In a study. Trusted Source.

Why is folate important during pregnancy?

Recommended folate intake increases during pregnancy and breastfeeding to fuel rapid growth and help prevent neural tube defects in the fetus. The most common causes of folate deficiency include an inadequate diet, alcoholism, and difficulties in absorbing foods that contain folate or folate itself.

Which countries require fortification of foods with folic acid?

Other countries that require fortification of certain foods with folic acid include Costa Rica, Chile, and South Africa.

What is the best source of folate?

The best sources of folate are green vegetables, legumes, and liver. One cup of some of the best natural food sources of folate contains the following amounts: Asparagus: 268 mcg. Beef liver: 290 mcg.

When did folic acid start being added to food?

In 1998 , the United States Food and Drug Administration (FDA) and the Canadian government began requiring that manufacturers add folic acid to certain foods, including enriched bread, cereals, flours, cornmeal, pasta, rice, and other grain products.

What are the benefits of folic acid?

Well, as already mentioned above, the folic acids will help the body to stimulate the production of hemoglobin in the blood. Then, this hemoglobin will helps your body to create new cells from amino acid building blocks, which then will transform that into the body mass. 15. Beneficial For Chronic Kidney Disease.

Why is folic acid important?

Folic acid will be very essential to keep the health of your heart. Folic acid is widely known as the creator of amino acids. In this case, folic acid will help to metabolize homocysteine into methionine, which is one of the amino acids.

Why is it important to take folic acid while pregnant?

Consuming enough folic acid during the pregnancy will be beneficial to make sure that they will go through the healthy pregnancy and maintain the normal development of the fetus. So, consuming enough folic acids when you’re pregnant will protect you and your baby from a disease called neural tube defect.

How long does it take for folic acid to help with cervical dyslapsia?

evidence that patients with moderate levels of cervical dyslapsia shown a significant improvement related to their cervix’s condition after taking folic acids supplements regularly for about three months.

Does folic acid help Alzheimer's?

As already described above, the folic acid will metabolize the homocysteine in methionine, which this move will prevent the excessive amount of homocysteine. Many experimental studies already proved the efficacy of the folic acid to protect you from Alzheimer.

Is folic acid good for you?

Folic acids turn out to be very good for your brain since it will prevent you from brain diseases associated with Alzheimer. Many researchers have found that homocysteine once again play a vital role on why you can suffer from the diseases associated with your brain like dementia and Alzheimer. As already described above, the folic acid will metabolize the homocysteine in methionine, which this move will prevent the excessive amount of homocysteine.

Does folic acid reduce carcinogens?

In a study conducted on animal, many researchers found out that the addition of moderate amount of folic acids will reduce the carcinogens. Meanwhile, the addition of excess folic acids turns out will increase the growth of the tumor in the body.

What is the purpose of folate?

Folic acid is also sold in concentrated form in dietary supplements. Your body uses folate for a wide array of critical functions, including ( 1. Trusted Source.

What is the most commonly used folate?

There are many derivatives of folate. However, folinic acid, folic acid, and 5-methyltetrahydrofolate are the most widely used in dietary supplements. Folinic acid is a naturally occurring folate that’s found in foods and commonly known as leucovorin in the clinical setting.

What is folic acid?

Folic acid is a synthetic, water-soluble vitamin used in supplement s and fort ified foods.

How much folic acid is in a multivitamin?

Dosages vary widely, but most supplements deliver around 680–1,360 mcg DFE (400–800 mcg of folic acid) ( 7 ).

How much folic acid should I take a day for Alzheimer's?

A 2019 study in 180 adults with mild cognitive impairment (MCI) demonstrated that supplementing with 400 mcg of folic acid per day for 2 years significantly improved measures of brain function, including verbal IQ and reduced blood levels of certain proteins involved in the development and progression of Alzheimer’s disease, compared with a control group ( 13 ).

What causes low folate levels?

Folate deficiency has multiple causes, including: 1 poor dietary intake 2 diseases or surgeries that affect folate absorption in the digestive system, including celiac disease, gastric bypass, and short bowel syndrome 3 achlorhydria or hypochlorhydria (absent or low stomach acid) 4 drugs that affect folate absorption, including methotrexate and sulfasalazine 5 alcoholism 6 pregnancy 7 hemolytic anemia 8 dialysis

What are the derivatives of folate?

There are many derivatives of folate. However, folinic acid, folic acid, and 5-methyltetrahydrofolate are the most widely used in dietary supplements.

What are the diseases that folate is used for?

This section focuses on seven diseases and disorders in which folate might play a role: autism spectrum disorder; cancer; cardiovascular disease and stroke; dementia, cognitive function, and Alzheimer’s disease; depression; NTDs; and preterm birth, congenital heart defects, and other congenital anomalies.

What is the most important folate-dependent reaction?

One of the most important folate-dependent reactions is the conversion of homocysteine to methionine in the synthesis of S-adenosyl-methionine, an important methyl donor. Another folate-dependent reaction, the methylation of deoxyuridylate to thymidylate in the formation of DNA, is required for proper cell division.

What foods are high in folate?

Includes a variety of protein foods such as lean meats; poultry; eggs; seafood; beans, peas, and lentils; nuts and seeds; and soy products. Beef liver contains high amounts of folate. Peas, beans, nuts, and eggs also have folate. Limits foods and beverages higher in added sugars, saturated fat, and sodium.

When did the FDA start adding folic acid to bread?

In January 1998, the U.S. Food and Drug Administration (FDA) began requiring manufacturers to add 140 mcg folic acid/100 g to enriched breads, cereals, flours, cornmeals, pastas, rice, and other grain products [ 13] to reduce the risk of neural tube defects (NTDs).

Which vitamins lower homocysteine levels?

Folate and other B vitamins are involved in homocysteine metabolism, and researchers have hypothesized that these micronutrients reduce cardiovascular disease risk by lowering homocysteine levels [ 1, 84 ]. Folic acid (and vitamin B12) supplements lower homocysteine levels.

Is folic acid a B vitamin?

Folate is a water-soluble B vitamin that is naturally present in some foods, added to others, and available as a dietary supplement. “Folate,” formerly known as “folacin” and sometimes “vitamin B9,” is the generic term for naturally occurring food folates, and folates in dietary supplements and fortified foods, including folic acid. Food folates are in the tetrahydrofolate (THF) form and usually have additional glutamate residues, making them polyglutamates [ 1 ]. Folic acid is the fully oxidized monoglutamate form of the vitamin that is used in fortified foods and most dietary supplements. Some dietary supplements also contain folate in the monoglutamyl form, 5-methyl-THF (also known as L-5- MTHF, 5-MTHF, L-methylfolate, and methylfolate).

Does alcohol affect folate absorption?

Moreover, alcohol interferes with folate absorption and hepatic uptake, accelerates folate breakdown, and increases its renal excretion [ 1, 4, 9 ]. An evaluation in Portugal, where the food supply is not fortified with folic acid, found low folate status in more than 60% of people with chronic alcoholism [ 34 ].

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